In 1981 her first exhibition featuring strip-tease artists and acrobats appeared at the Centre Pompidou and at the Galerie Texbraun in Paris. Encouraged by the success of her first show, Rheims produced a series of images of stuffed animals which were also exhibited in Paris and later in New York.
Rheims continues to shoot beautiful photographs and to publish books. Additionally she has worked on editorials for magazines such as Elle, L’Officiel, Citizen K, Tatler, 10 magazine and Marie Claire. She has also shot advertising campaigns for Chanel, Lancôme, Diane Von Furstenberg, Bebe and Well.